Head of Supply Chain TMabs – Genzyme – Westborough, MA, USA
Genzyme has pioneered the development and delivery of transformative therapies for patients affected by rare and debilitating diseases for over 30 years. We accomplish our goals through world-class research, collaboration with the global patient community, and with the compassion and commitment of our employees. With a focus on rare diseases and multiple sclerosis, we are dedicated to making a positive impact on the lives of the patients and families we serve. Genzyme’s portfolio of transformative therapies, which are marketed in countries around the world, represent groundbreaking and life-saving advances in medicine. As a Sanofi company, Genzyme benefits from the reach and resources of one of the world’s largest pharmaceutical companies, with a shared commitment to improving the lives of patients.
Sanofi, an integrated global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients’ needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and the new Genzyme.
Genzyme Corporation (a Sanofi company) and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status, or any other characteristics protected by applicable law.
Head of Supply Chain TmAbs
. This mission is to lead a system of product master planning and business practices to conduct and oversee operations planning for end-to-end (E2E) T-MAbs internal or external manufacturing and testing operations/sites, and identify budget & S&OP capacity & resources required to meet T-MAbs Drug Substance (DS)/Drug Product (DP)/Devices production target for Sanofi pipelines, Regeneron alliance and/or other CMO partners.
. The position leads management and execution of the materials transactions for T-MAbs DS manufacturing and testing operations/sites, including the replenishment of direct & indirect materials and inventory (critical materials, intermediates, DS), and also oversees the overall E2E T-MAbs Product Master Sites Planning/MRP/S&OP/LRP function (clinical & commercial) and site capacity models (DS/DP/Devices).
. The role develops budgets for OpEx, labor and capital expenditures for Materials Management and directs the allocation of resources to meet financial performance requirements. The position provides functional and/or direct leadership and direction through T-MAbs DS/DP/Devices related site Supply Chain (SC) managers or professional staff when/where relevant.
. The role will operate by direct management of the SC function for the DS supply nodes and by influence to ensure fully integrated and coordinated planning along the E2E supply chain.
. The role will recruit and manage a team of four people:
- E2E Integrated Planning Director
- Supply Management Director
- Materials Management Director
- SC Project/Process Lead (cold chain, storage, etc…)
Lead directly the sites DS Supply Chain managers to provide overall production plan metrics with respect to product/campaign management and capabilities, gather data and analyze key performance metrics including total operation cycle time from small scale to formulated bulk release. Identify reasons for missed OTIF (On-Time-In-Full) and initiate problem resolution.
Manage key SC processes and tools (standard and simulation) to support DS operations planning (MRP II, S&OP, central data base, Marco inventory, DS International flows, customs, etc…).
Responsible for long/short term capacity analysis and planning of available operations times for each product value stream; manage all Life cycle Management (LCM) changes (new products, regulatory changes, post approval submissions, transfers) in the T-MAbs Sites that impact direct materials, equipment, facilities, materials replenishment, finite scheduling, and kitting.
Monitor and control the DS production schedule adherence and alert when actual or projected output deviations and capability bottlenecks.
Responsible for safe and compliant short term materials storage and materials movement operations.
Maintain proper inventory levels and control costs (direct and indirect materials replenishment), and define relevant stock policies depending on product flows and process risk management.
Responsible for the direct materials ordering process through vendors and external partners ensuring timely materials movement/status transactions and the cycle counting process; close interaction with strategic supply and purchasing structure.
Drive and oversee customer service excellence and interactions with all relevant supplying entities.
Drive and oversee E2E T-MAbs product DS/DP/Devices SC performance (dashboard, trends, KPI’s), projects management and continuous improvement initiatives within the planning and materials functions.
Work collaboratively within the value stream, with Global Biologics Strategic Supply & Sourcing (3S) Structure colleagues, as well as other Global organizations when/where appropriate: Biologics Platform, Injectable Platform, Devices Platform, Finance, Quality, Regulatory, Procurement and Supply Chain.
Providing effective leadership including: developing and implementing objectives and business strategies; selecting key personnel and motivating members of the functional area; challenging employees to develop as leaders while serving as a role model and mentor; assisting with performance calibration/talent pool management/succession planning; individual goal setting/performance reviews; training and development; supporting workforce diversity, quality and safety and supporting supervisors/managers in the management of their employees/department which support achievement of individual department/business objectives.
Ensuring compliance with all legal and business requirements and Sanofi policies and practices.
Establishing departmental and individual goals and objectives in alignment with site goals and priorities.
Identifying performance improvement targets and metrics. Ensuring capabilities and capacity in place to effectively deliver on all departmental commitments and performance targets.
Strengthening overall leadership and organizational capabilities in area of responsibility. Building and sustaining high performance management team and ensuring strong alignment and coordination with other functional groups at the site.
Identifying the required resources and expertise, implementing the appropriate team/departmental structures and establishing the required processes and communications to enable department(s) to effectively deliver on all commitments while building a culture of Safety and Quality and continuous improvement.
Identifying and communicating risks in area of responsibility and across the site; creating strategies and plans to manage risk to the operations.
Participating in development of site long range in line with the corporate long range planning.
Ensuring effective utilization of resources by ensuring robust employee development, performance management, succession planning, and rewards and recognitions practices in area of responsibility.
Managing headcount and expenses in area of responsibility to meet approved spending plan while achieving all departmental commitments and project objectives.
Motivating, retaining and developing key employees. Building and sustaining employee engagement by creating an environment within which individuals and teams can excel.
Interacting closely with E2E Product Supply Chain Leaders (Global Biologics 3S Structure), relevant Drug Product sites and functions to define production plans, yearly goals and budgets for reporting functions and operations as well as long range plans (LRP and LRCP).
Bachelor’s degree or equivalent in a science or technical field, or supply chain operations, and minimum 15 years of experience in biologics/pharmaceuticals or a related industry, with 7 years in management position or an equivalent combina tion of education and experience.
Knowledge and experience of Biologics product launches is a distinct advantage.
Strong understanding and experience of materials operations (flow management, transportation…) planning and purchasing systems in a CGMP manufacturing environment and document management systems
Experience using ERP systems and SAP strongly desired, with a good understanding of all the links between information flows, materials flows and financial flows
Project management skills and good knowledge of supply chain theory and practice
Strong knowledge and understanding of biopharmaceutical CGMP manufacturing preferably in large scale commercial biologics manufacturing required. Solid understanding of quality, supply chain, finance, procurement, regulatory and planning functions
Knowledgeable of requirements for post approval changes and information typically found in all regulatory submission documents
Knowledge and experience with discrepancy investigations and lot dispositions
Understanding of business requirements and customer structure, especially key markets
Skilled in achieving results and managing others to achieve corporate, site, and departmental objectives
Excellent communication skills, good overall presentation and influencing skills, assertiveness and ability to interact and gain support of senior management
Leadership skills: ability to organize, motivate and lead through influence and direct/indirect impact, coach and develop talents
Experience with budgeting and long range planning
Autonomous, used to work transversally and internationally, agree to travel significantly (mainly North America and Europe)
Fluent in English, French and German preferred as a plus
Key Expected Leadership Behaviors:
Trust, Passion, Respect, Empower with Accountability, Collaborate Transversally, Bias for Action, Decisive
Job : Production
Primary Location : United States-Massachusetts-Westborough