Infographic – The Evolution of Cold Chain Innovation
In the early days of temperature-controlled transport for pharmaceutical products, shippers used expanded polystyrene with water-based gel paks. This packaging would be validated for a specific time period and temperature range. Though inexpensive, Styrofoam packaging — even with passive temperature control inserts — often resulted in temperature excursions during shipping or storage. Logistics providers had to make a lot of assumptions about whether or not a product or sample stayed in temperature range during transport, and manufacturers and trial sponsors experienced delays due to damaged product.